About this Course

This course is a journey into the biology of the human genome and will highlight the scientific, social, and personal perspectives of people living with a variety of traits.

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Course Cost
Free
Timeline
Approx. 3 months
Skill Level
Beginner
Included in Course
  • Rich Learning Content

  • Interactive Quizzes

  • Taught by Industry Pros

  • Self-Paced Learning

  • Student Support Community

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Free Course

Tales from the Genome

by 23andMe

Enhance your skill set and boost your hirability through innovative, independent learning.

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Course Leads

  • Joanna Mountain
    Joanna Mountain

    Instructor

  • Uta Francke
    Uta Francke

    Instructor

  • 23andMe Team
    23andMe Team

    Instructor

  • Matthew Cook
    Matthew Cook

    Instructor

  • Lauren Castellano
    Lauren Castellano

    Instructor

What You Will Learn

Lesson 1

Introduction to traits and heredity

  • Trait variation and categorization.
  • Basic models of inheritance.
  • The connection via DNA.
Lesson 1

Introduction to traits and heredity

  • Trait variation and categorization.
  • Basic models of inheritance.
  • The connection via DNA.
Lesson 2

Defining the genome

  • DNA structure and chromosomes.
  • The genome organization.
Lesson 2

Defining the genome

  • DNA structure and chromosomes.
  • The genome organization.
Lesson 3

How a genome works

  • Protein coding genes, transcription, translation.
  • Discerning the genetic code and alleles.
Lesson 3

How a genome works

  • Protein coding genes, transcription, translation.
  • Discerning the genetic code and alleles.
Lesson 4

Gene regulation

  • Non-coding DNA and regulatory regions of genes.
  • Transcription factors.
Lesson 4

Gene regulation

  • Non-coding DNA and regulatory regions of genes.
  • Transcription factors.
Lesson 5

Transmission of genes and traits

  • Family relationships and pedigrees.
  • Inheritance patterns, allele dominance.
  • Chromosome dynamics.
Lesson 5

Transmission of genes and traits

  • Family relationships and pedigrees.
  • Inheritance patterns, allele dominance.
  • Chromosome dynamics.
Lesson 6

Origin of mutation/variation

  • Types of mutations and various causes of mutation.
  • Allelic frequency, and the spread of alleles in a population.
Lesson 6

Origin of mutation/variation

  • Types of mutations and various causes of mutation.
  • Allelic frequency, and the spread of alleles in a population.
Lesson 7

How to obtain and interpret personal genetic information

  • Personalized genetics: sample acquisition, DNA extraction and processing.
  • Interpretation of results.
Lesson 7

How to obtain and interpret personal genetic information

  • Personalized genetics: sample acquisition, DNA extraction and processing.
  • Interpretation of results.
Lesson 8

Simple genetic traits

  • Molecular causes of monogenic traits.
  • Loss-of-function vs. gain-of-function alleles, and dominance.
Lesson 8

Simple genetic traits

  • Molecular causes of monogenic traits.
  • Loss-of-function vs. gain-of-function alleles, and dominance.
Lesson 9

Multifactorial traits

  • Polygenic traits, qualitative and quantitative measures.
  • Twin studies, relative risk, and genome-wide association studies (GWAS).
Lesson 9

Multifactorial traits

  • Polygenic traits, qualitative and quantitative measures.
  • Twin studies, relative risk, and genome-wide association studies (GWAS).
Lesson 10

Pharmacogenetics: genes and drugs

  • Pharmacokinetics and pharmacodynamics.
  • Alleles affecting drug metabolism.
  • Personalized medicine.
Lesson 10

Pharmacogenetics: genes and drugs

  • Pharmacokinetics and pharmacodynamics.
  • Alleles affecting drug metabolism.
  • Personalized medicine.

Prerequisites and Requirements

No previous experience in genetics is necessary. However, familiarity with basic biological concepts, like the cell, is beneficial.

See the Technology Requirements for using Udacity.

Why Take This Course

You will learn about fundamental principles of inheritance, gene expression, mutation and variation, development of simple and complex biological traits, human ancestry and evolution, and the acquisition of personal genetic information. By the end of this course, you will be able to read and understand genetic information available from personal genetics services such as 23andMe.

What do I get?
  • Instructor videos
  • Learn by doing exercises
  • Taught by industry professionals
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